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Magnesium (HVP chelate)
Magnesium is the “zen” molecule. It is a mineral essential to the body's proper functioning. Its main property is its action on the nervous system, but it has many other benefits, notably for muscles, the heart, bones and the immune system. It is particularly recommended for people suffering from stress or deficiency. Involved in numerous metabolic reactions and the transmission of nerve signals, magnesium is essential for maintaining a regular heartbeat, lipid metabolism, as well as regulating blood sugar levels and blood pressure. Magnesium also helps prevent cardiovascular disease, migraines, diabetes, severe asthma, difficulty sleeping, premenstrual pain and pre-eclampsia. Caused by a diet low in magnesium, stress, consumption of energy drinks and long-term use of certain medications (diuretics, certain antibiotics, immunosuppressants, oral contraceptives, estrogens and certain anti-cancer drugs), magnesium deficiency is difficult to diagnose1. validated by clinical trials, taking magnesium as a dietary supplement is recognized in the treatment of a number of disorders, including cardiovascular disease, migraines, diabetes, severe asthma, premenstrual syndrome and pre-eclampsia1.
Vitamin B6 (Pyridoxine HCL)
A daily intake of vitamin B6 is essential, as the body can neither produce nor accumulate this vitamin. It plays a role in the synthesis of certain antibodies and hemoglobin, and in maintaining mental equilibrium. It contributes to the proper absorption of vitamin B12 and the assimilation of magnesium by the body. According to the Society of Obstetricians and Gynaecologists of Canada (SOGC), more than half of all pregnant women suffer from nausea and vomiting. The origin of this discomfort is not clearly defined, but a serious clue, concerning vitamin B6 levels in the blood, seems to correlate with the onset and severity of the disorders. The antiemetic effect of vitamin B6 has been known since 1942. Its effectiveness in preventing nausea during pregnancy has since been confirmed by numerous clinical trials.
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Why choose Prozen?
This supplement is indicated for patients suffering from disorders associated with magnesium and vitamin B6 deficiency in men and women (nervous and/or muscular fatigue, irritability, transient tiredness, minor sleep disorders, palpitations, muscle cramps, tingling, pain associated with premenstrual syndrome, menstruation and migraines). The combination of vitamin B6 and magnesium may be more effective (than either treatment alone) against PMS symptoms.
Also indicated for pregnant women with pregnancy-related morning sickness, stress and fatigue.
How do I take my treatment?
1 capsule 3 times a day, with food a few hours before or after taking other medications.
How long should I take Prozen?
Prozen is a natural supplement that should be taken on a daily basis for an indefinite period of time. We therefore recommend that you make it part of your daily routine.
When should I stop taking Prozen?
Prozen can be taken daily for an indefinite period. However, it is important to stop taking it if your doctor recommends it.
Use of this supplement may be considered during pregnancy, if necessary. Ask your doctor or pharmacist for advice.
It is recommended not to exceed 20mg/day of vitamin B6 for breast-feeding women. Ask your doctor or pharmacist for advice.
Some people may develop diarrhea.
Contraindicated in cases of severe renal insufficiency (impaired kidney function).
- de Baaij, J. H., Hoenderop, J. G. & Bindels, R. J. Magnesium in man: implications for health and disease. Physiol Rev 95, 1-46, doi:10.1152/physrev.00012.2014 (2015).
- Rosanoff A, Weaver CM, Rude RK. Suboptimal magnesium status in the United States: are the health consequences underestimated? Nutr Rev. Mar 2012;70(3):153-64. doi:10.1111/j.1753-4887.2011.00465.x
- 3 Barbagallo M, Dominguez LJ. Magnesium and aging. Curr Pharm Des. 2010;16(7):832-9. doi:10.2174/138161210790883679
- 4 Boyle NB, Lawton C, Dye L. The Effects of Magnesium Supplementation on Subjective Anxiety and Stress-A Systematic Review. Nutrients. Apr 26 2017;9(5)doi:10.3390/nu9050429
- 5 Jacka FN, Overland S, Stewart R, Tell GS, Bjelland I, Mykletun A. Association between magnesium intake and depression and anxiety in community-dwelling adults: the Hordaland Health Study. Aust N Z J Psychiatry. Jan 2009;43(1):45-52. doi:10.1080/00048670802534408
- 6 Przybelski AG, Bendlin BB, Jones JE, Vogt NM, Przybelski RJ. Vitamin B6 and vitamin D deficiency co-occurrence in geriatric memory patients. Alzheimers Dement (Amst). Jan-Mar 2024;16(1):e12525. doi:10.1002/dad2.12525
- 7 Camfield DA, Wetherell MA, Scholey AB, et al. The effects of multivitamin supplementation on diurnal cortisol secretion and perceived stress. Nutrients. Nov 11 2013;5(11):4429-50. doi:10.3390/nu5114429
- 8 Wyatt KM, Dimmock PW, Jones PW, Shaughn O'Brien PM. Efficacy of vitamin B-6 in the treatment of premenstrual syndrome: systematic review. Bmj. May 22 1999;318(7195):1375-81. doi:10.1136/bmj.318.7195.1375
- 9 Combs Jr GF, McClung JP. The vitamins: fundamental aspects in nutrition and health. Academic press; 2016.
- 10 Noah L, Dye L, Bois De Fer B, Mazur A, Pickering G, Pouteau E. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial. Stress Health. Dec 2021;37(5):1000-1009. doi:10.1002/smi.3051