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Ubiquinol
Ubiquinol is the most biologically active form of coenzyme Q10. Coenzyme Q10 is a vitamin-like substance that serves
as an energy source and antioxidant. It is a substance naturally produced by the body, but its quantity gradually
diminishes with age. Ubiquinol's role in cellular energy production and its powerful antioxidant capacity make it an
essential component in supporting the body's natural processes throughout the aging process. Ubiquinol
supplementation, known for its high bioavailability in the form of CoQ10, has shown promise in restoring ovarian
reserve and improving egg quality, particularly in those over the age of
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VISIT OUR HEALTH RESOURCES SECTION TO LEARN MORE ABOUT THESE SPECIFIC INGREDIENTS
Why choose Ubiq?
Ubiquinol supplementation offers numerous health benefits. In men, CoQ10 is particularly beneficial for reproductive health, as it has been shown to improve sperm motility, density and morphology, DNA fragmentation levels and overall fertility7. In women, studies have shown that CoQ10 is present in human follicular fluid and that its concentration is significantly higher in mature oocytes than in abnormal ones, suggesting a positive correlation between CoQ10 levels in follicular fluid and oocyte quality4,16. Ubiquinol may also improve mitochondrial function in the oocyte, leading to a reduction in aneuploidy rates and improved embryo quality.
Beyond reproductive health, ubiquinol supplementation can improve glycemic control in people with type 2 diabetes, suggesting benefits for metabolic health13.
Ubiquinol may also increase plasma and cellular antioxidant levels, which is crucial for combating oxidative stress, a factor encountered in many chronic diseases, including cardiovascular disease18.
Our supplement is therefore designed for adults who wish to proactively manage age-related decline in reproductive function and improve cardiovascular health with a natural, bioavailable nutrient.
How do I take my treatment?
2 to 3 capsules 1 time a day with food, a few hours before or after taking other medications.
How long should I take Ubiq?
We recommend a course of treatment lasting 3 to 6 months, renewable if necessary.
We encourage our patients to follow a minimum 3-month course of treatment to observe profound changes and give the body time to find a new equilibrium.
It is ideal to start the treatment 3 to 6 months before the start of fertility treatments.
When should I stop taking Ubiq?
Ubiq can be stopped as soon as pregnancy is confirmed.
Consult a health care professional before use if you are pregnant or breastfeeding, or if you are taking blood-thinning or anticoagulant medication.
- Faddy MJ. Follicle dynamics during ovarian ageing. Mol Cell Endocrinol. 2000 May 25;163(1-2):43-8.
- O'Connor KA, Holman DJ, Wood JW. Declining fecundity and ovarian ageing in natural fertility populations. Maturitas. 1998 Oct 12;30(2):127-36.
- Ben-Meir A, Burstein E, Borrego-Alvarez A, et al. Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging. Aging Cell. 2015 Oct;14(5):887-95.
- Bates A, Shen Q, Hiebert JB, et al. Myocardial energetics and ubiquinol in diastolic heart failure. Nurs Health Sci. 2014 Dec;16(4):428-33.
- Ernster L, Dallner G. Biochemical, physiological and medical aspects of ubiquinone function. Biochim Biophys Acta. 1995 May 24;1271(1):195-204.
- Xu Y, Nisenblat V, Lu C, et al. Pretreatment with coenzyme Q10 improves ovarian response and embryo quality in low-prognosis young women with decreased ovarian reserve: a randomized controlled trial. Reproductive Biology and Endocrinology. 2018 2018/03/27;16(1):29.
- Mortensen SA, Rosenfeldt F, Kumar A, et al. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial. JACC Heart Fail. 2014 Dec;2(6):641-9.
- Rosenfeldt FL, Haas SJ, Krum H, et al. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum Hypertens. 2007 Apr;21(4):297-306.
- 4 Turi A, Giannubilo SR, Brugè F, et al. Coenzyme Q10 content in follicular fluid and its relationship with oocyte fertilization and embryo grading. Archives of gynecology and obstetrics. 2012;285:1173-1176.
- 5 Bentov Y, Hannam T, Jurisicova A, et al. Coenzyme Q10 Supplementation and Oocyte Aneuploidy in Women Undergoing IVF-ICSI Treatment. Clin Med Insights Reprod Health. 2014;8:31-6.
- 6 Meldrum DR, Casper RF, Diez-Juan A, et al. Aging and the environment affect gamete and embryo potential: can we intervene? Fertil Steril. 2016 Mar;105(3):548-559.
- 7 Abad C, Amengual MJ, Gosálvez J, et al. Effects of oral antioxidant treatment upon the dynamics of human sperm DNA fragmentation and subpopulations of sperm with highly degraded DNA. Andrologia. 2013 Jun;45(3):211-6.
- 8 Balercia G, Mancini A, Paggi F, et al. Coenzyme Q10 and male infertility. J Endocrinol Invest. 2009 Jul;32(7):626-32.
- 9 Mancini A, Balercia G. Coenzyme Q(10) in male infertility: physiopathology and therapy. Biofactors. 2011 Sep-Oct;37(5):374-80.
- 10 Singh RB, Niaz MA, Rastogi V, Rastogi SS. Coenzyme Q in cardiovascular disease. J Assoc Physicians India. 1998 Mar;46(3):299-306.
- 13 Mezawa M, Takemoto M, Onishi S, et al. The reduced form of coenzyme Q10 improves glycemic control in patients with type 2 diabetes: An open label pilot study. BioFactors. 2012;38(6):416-421.
- 16 Giannubilo SR, Orlando P, Silvestri S, et al. CoQ10 supplementation in patients undergoing IVF-ET: The relationship with follicular fluid content and oocyte maturity. Antioxidants. 2018;7(10):141.
- 18 Orlando P, Silvestri S, Galeazzi R, et al. Effect of ubiquinol supplementation on biochemical and oxidative stress indexes after intense exercise in young athletes. Redox Rep. 2018 Dec;23(1):136-145.
- Co-enzyme Q10 supplementation improves ovarian response and mitochondrial function in aged mice. Fertility and Sterility Vol. 92, Issue 3. E. Burstein, A. Perumalsamy, Y. Bentov, N. Esfandiari, et al.
- CoQ10 treatment can improve fertility and oocyte quality in old mice. Fertility and Sterility Vol. 96, Issue 3. A. Ben-Meir, J. Chong, A. Borrego-Alvarez, K.H. Moley,et al.
- Littarru GP, Brugè F, Tiano L, editors. Biochemistry of Coenzyme Q102017.