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Fertil Pro® men + L-Carnitine
Β-carotene: provitamin A, retinol
β-carotene is a precursor nutrient of vitamin A. It belongs to the carotenoid family. The various stages of sperm maturation require vitamin A5. It plays an essential role in normal testicular sperm production. Vitamin A deficiency has been observed in men with low sperm motility6,7. It's important to note that carotenoids work synergistically with Vitamin E, present in our basic male fertility formula (Fertil pro® men + L-Carnitine).
Coenzyme Q10: ubiquinone-10, ubidecarenone
Coenzyme Q10 is a powerful antioxidant molecule that is important for male fertility. CoQ10 deficiency is known to be correlated with poor sperm motility3. Clinical trials have validated that dietary supplementation with CoQ10 can restore its levels in the seminal fluid and spermatozoa of infertile patients, in whom low sperm motility had been detected. This restoration is accompanied by a significant increase in sperm motility3,4.
Lycopene
Lycopene is a powerful antioxidant found in plants. It also belongs to the carotenoid family, which is recognized for its synergistic action with vitamin E. Lycopene plays an important role in protecting spermatozoa against oxidative stress8. Normally present in high quantities in the testicles and seminal fluid, its content appears to be reduced in men suffering from infertility of unknown origin1,9,11. In addition, a clinical study validated that dietary supplementation with lycopene could improve sperm motility and increase fertility potential in men12.
Vitamin D: cholecalciferol (vitamin D3) or ergocalciferol (vitamin D2)
Vitamin D is a non-essential dietary vitamin that plays an important role in maintaining bone health and overall health. However, in men, vitamin D status is associated with sperm quantity, quality, morphology and motility13,14. Vitamin D supplementation is known to enhance sperm quality, thus improving the chances of conception15,16.
VISIT OUR HEALTH RESOURCES SECTION TO LEARN MORE ABOUT THESE SPECIFIC INGREDIENTS
Why choose Fertil Pro® MTL?
A low nutritional intake of antioxidants is associated with sperm oxidative stress1. Oxidative stress damage affects sperm motility, the ability to recognize the egg and the ability to fuse with it2. Medically recognized, a positive correlation exists between seminal fluid levels of vitamin A, CoQ10, Lycopene, Vitamin D and sperm motility3,4. Fertil Pro® MTL is a formula specially designed for men with low sperm motility and should be taken in conjunction with our basic male fertility formula Fertil Pro® men + L-Carnitine.
How do I take my treatment?
1 capsule daily with meal, a few hours before or after taking other medication.
How long should I take Fertil Pro® MTL?
We recommend a course of treatment lasting 3 to 6 months, renewable if necessary.
We encourage our patients to follow a cure of at least 3 months to observe profound changes and give the body time to find a new equilibrium.
It is ideal to start treatment 2 to 3 months before fertility treatments.
When should Fertil Pro® MTL be stopped?
There is no contraindication to continuing Fertil Pro® MTL during fertility treatments.
Fertil Pro® MTL should be taken in addition to our Fertil Pro® men + L-Carnitine formula. These two supplements are available as a combo.
Consult a healthcare professional before use if you are taking blood pressure medication or anticoagulants.
- Kao, S. H. et al. Increase of oxidative stress in human sperm with lower motility. Fertil Steril 89, 1183-1190, doi:10.1016/j.fertnstert.2007.05.029 (2008).
- Palan, P. & Naz, R. Changes in various antioxidant levels in human seminal plasma related to immunoinfertility. Arch Androl 36, 139-143 (1996).
- 1 Mendiola, J. et al. A low intake of antioxidant nutrients is associated with poor semen quality in patients attending fertility clinics. Fertil Steril 93, 1128-1133, doi:10.1016/j.fertnstert.2008.10.075 (2010).
- 3 Balercia, G. et al. Coenzyme Q10 treatment in infertile men with idiopathic asthenozoospermia: a placebo-controlled, double-blind randomized trial. Fertil Steril 91, 1785-1792, doi:10.1016/j.fertnstert.2008.02.119 (2009).
- 4 Balercia, G. et al. Coenzyme Q(10) supplementation in infertile men with idiopathic asthenozoospermia: an open, uncontrolled pilot study. Fertil Steril 81, 93-98 (2004).
- 5 Endo, T. et al. Periodic retinoic acid-STRA8 signaling intersects with periodic germ-cell competencies to regulate spermatogenesis. Proc Natl Acad Sci U S A 112, E2347-2356, doi:10.1073/pnas.1505683112 (2015).
- 6 Omu, A. E., Fatinikun, T., Mannazhath, N. & Abraham, S. Significance of simultaneous determination of serum and seminal plasma alpha-tocopherol and retinol in infertile men by high-performance liquid chromatography. Andrologia 31, 347-354 (1999).
- 7 Ahmad, M. K. et al. Effect of Mucuna pruriens on semen profile and biochemical parameters in seminal plasma of infertile men. Fertil Steril 90, 627-635, doi:10.1016/j.fertnstert.2007.07.1314 (2008).
- 8 Zini, A., San Gabriel, M. & Libman, J. Lycopene supplementation in vitro can protect human sperm deoxyribonucleic acid from oxidative damage. Fertil Steril 94, 1033-1036, doi:10.1016/j.fertnstert.2009.04.004 (2010).
- 9 Agarwal, A. & Sekhon, L. H. The role of antioxidant therapy in the treatment of male infertility. Hum Fertil (Camb) 13, 217-225, doi:10.3109/14647273.2010.532279 (2010).
- 11 Zareba, P. et al. Semen quality in relation to antioxidant intake in a healthy male population. Fertil Steril 100, 1572-1579, doi:10.1016/j.fertnstert.2013.08.032 (2013).
- 12 Gupta, N. P. & Kumar, R. Lycopene therapy in idiopathic male infertility--a preliminary report. Int Urol Nephrol 34, 369-372 (2002).
- 13 Anagnostis, P., Karras, S. & Goulis, D. G. Vitamin D in human reproduction: a narrative review. Int J Clin Pract 67, 225-235, doi:10.1111/ijcp.12031 (2013).
- 14 Foresta, C. et al. Bone mineral density and testicular failure: evidence for a role of vitamin D 25-hydroxylase in human testis. J Clin Endocrinol Metab 96, E646-652, doi:10.1210/jc.2010-1628 (2011).
- 15 Ramlau-Hansen, C. H., Moeller, U. K., Bonde, J. P., Olsen, J. & Thulstrup, A. M. Are serum levels of vitamin D associated with semen quality? Results from a cross-sectional study in young healthy men. Fertil Steril 95, 1000-1004, doi:10.1016/j.fertnstert.2010.11.002 (2011).
- 16 Blomberg Jensen, M. et al. Vitamin D is positively associated with sperm motility and increases intracellular calcium in human spermatozoa. Hum Reprod 26, 1307-1317, doi:10.1093/humrep/der059 (2011).
- Mohammad Reza Safarinejad. Efficacy of coenzyme Q10 on semen parameters, sperm function and reproductive hormones in infertile men. J Urol . 2009 Jul;182(1):237-48.
- Anuj Goyal, Mridula Chopra, Bashir A Lwaleed, Brian Birch, Alan J Cooper. The effects of dietary lycopene supplementation on human seminal plasma. BJU Int . 2007 Jun;99(6):1456-60.