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Acetyl-l-carnitine (acetyl-l-carnitine hcl)
Acetyl-L Carnitine is a powerful antioxidant that facilitates the transport of fatty acids into the mitochondria, enhancing energy production essential for optimal sperm function7. Studies confirm a direct correlation between L-Carnitine levels in semen and improved sperm parameters such as concentration, motility and morphology, underlining its importance in male fertility8,13,14. In addition, its involvement in the sperm maturation process in the epididymisis crucial for ensuring sperm quality and viability8,10.
Vitamin C (ascorbic acid)
Vitamin C is an antioxidant that has been shown to reduce DNA damage induced by reactive oxygen species (ROS) in semen15. Vitamin C has been reported to work effectively inconjunction with vitamin E and other antioxidants to improve sperm quality16. A daily intake of 200 to 1,000 mg of vitamin C is recommended to improve male fertility and sperm quality17-19.
Vitamin E (succinate)
Vitamin E is an antioxidant that maintains the viability of immature spermatozoa and contributes to theirmaturation along the epididymis20,21. In addition, clinical studies have demonstrated that vitamin E improves theability of spermatozoa to fertilize the egg22. A clear correlation has been observed between the concentration ofvitamin E in seminal fluid and the proportion of motile spermatozoa in a semen sample23.
Folic acid (folate, vitamin b9)
Folic acid is an essential B vitamin involved in nucleic acid synthesis and amino acid metabolism7. The use of folic acid in the management of male infertility is based on its ability to neutralize free radicals7. Folic acid intake in sub-fertile men has been linked to improved sperm count and motility24,25.
Vitamin B12 (methylcobalamin)
This vitamin is essential for spermatogenesis and the maintenance of normal sperm function, making it a crucial co-factor in male fertility26. Vitamin B12 has been shown to increase sperm count, improve sperm motility and reduce sperm DNA damage27. It also preserves glutathione, which modulates responses to oxidative stress28.
Zinc (gluconate)
Zinc plays a critical role in the structure and function of sperm DNA. It is essential for the organization of DNA, RNA and proteins, as well as for cell membrane stability and cell division29. Zinc supplementation in sperm media has been shown to protect against exogenous oxidative stress and improve support for embryonic development30. Zinc may also play a vital role in the activity of enzymes responsible for fertilization31.
Selenium (yeast extract)
Selenium is known to be a cofactor for several enzymes, including glutathione peroxidase, which is crucial for protecting cells against oxidative damage, a role that is likely to be beneficial for sperm quality too32. Selenium is also known to help maintain the structural integrity of spermatozoa, which is why selenium deficiency is often associated with abnormalities in sperm morphology and impaired sperm motility11,12.
VISIT OUR HEALTH RESOURCES SECTION TO LEARN MORE ABOUT THESE SPECIFIC INGREDIENTS

Why choose Fertil Pro® men + L-Carnitine?
Multiple clinical studies have highlighted the importance of vitamins and minerals in supporting sperm health. It has been shown that antioxidant-rich diets can alleviate oxidative stress, which is a predominant factor in male infertility5. Oxidative stress, which can be exacerbated by certain environmental and lifestyle choices, is known to induce both genetic mutations and functional deficits in spermatozoa6. L-Carnitine stands out as a robust antioxidantwhich is vital for energy metabolism in sperm cells, aiding their motility and overall vitality7. Clinical studies support the idea that regular supplementation with essential nutrients, in particular L-Carnitine, is beneficial for reproductive outcomes8-10. In addition, selenium and zinc, important for sperm structural integrity and function, and folic acid, which is crucial for DNA synthesis and repair, are also integral components of this formulation7,11,12.
Daily intake of nutrients, which have been shown to help in a large number of cases of unexplained hypofertility and sperm-related problems, could increase a couple's chances of conceiving.
These essential nutrients and minerals have been selected for formulation in Fertil Pro® men + L-Carnitine, which could improve sperm production and quality by reducing oxidative stress damage.
Taking this dietary supplement could have an impact on sperm quality and protect the integrity of the sperm's genetic information.
How do I take my treatment?
1 tablet 1 time a day. Take a few hours before taking other medications.
How long should I take Fertil Pro® men + L-Carnitine?
We recommend a course of treatment lasting a minimum of 3 months to observe profound changes and give the body time to find a new equilibrium, renewable if necessary.
It is ideal to start treatment 2 to 3 months before the start of fertility treatments.
When should I stop taking Fertil Pro® men + L-Carnitine?
Fertil Pro® men + L-Carnitine can be stopped as soon as pregnancy is confirmed.
Change in sperm
An improvement in sperm quality and quantity will be noticeable when taking Fertil Pro® men + L-Carnitine.
To optimize the benefits of Fertil Pro® men + L-Carnitine, we suggest coupling it with our Fertil Pro® MTL supplement. These two supplements are available as a combo.
As with any supplement, it's important to follow the recommended dosage to support optimal health. L-Carnitine and vitamin C, when taken in excess (> 3 g/day and > 2g/day, respectively), can lead to digestive discomfort1,2. Vitamin E contributes to reproductive health, but as a precaution, those taking anticoagulant medication should follow dosage guidelines3. Although folic acid is generally considered to be non toxic, it should be administered with caution to epileptic patients on medication, as seizure control may be affected4.
Zinc supplementation may cause copper deficiency.
Keep out of reach of children.
- Chawla J, Kvarnberg D. Chapter 59 - Hydrosoluble vitamins. In: Biller J, Ferro JM, editors. Handbook of Clinical Neurology. Vol. 120: Elsevier; 2014. p. 891-914.
Olson J. Carotenoids, Shils M, Olson J, Shike M, Ross Z. In. Modern Nutrition in Health. Baltimore, Williams & Wilkins; 1999. - Owen KN, Dewald O. Vitamin E Toxicity. StatPearls. Treasure Island (FL): StatPearls PublishingCopyright © 2023, StatPearls Publishing LLC.; 2023.
- Butterworth CE, Jr., Tamura T. Folic acid safety and toxicity: a brief review. Am J Clin Nutr. 1989 Aug;50(2):353-8.
- Skoracka K, Eder P, Łykowska-Szuber L, et al. Diet and Nutritional Factors in Male (In)fertility-Underestimated Factors. J Clin Med. 2020 May 9;9(5).
- Zini A, San Gabriel M, Baazeem A. Antioxidants and sperm DNA damage: a clinical perspective. J Assist Reprod Genet. 2009 Aug;26(8):427-32.
- Majzoub A, Agarwal A. Systematic review of antioxidant types and doses in male infertility: Benefits on semen parameters, advanced sperm function, assisted reproduction and live-birth rate. Arab J Urol. 2018 Mar;16(1):113-124.
- Mateus FG, Moreira S, Martins AD, et al. L-Carnitine and Male Fertility: Is Supplementation Beneficial? J Clin Med. 2023 Sep 6;12(18).
- Kopets R, Kuibida I, Chernyavska I, et al. Dietary supplementation with a novel l-carnitine multi-micronutrient in idiopathic male subfertility involving oligo-, astheno-, teratozoospermia: A randomized clinical study. Andrology. 2020 Sep;8(5):1184-1193.
- Agarwal A, Said TM. Carnitines and male infertility. Reproductive BioMedicine Online. 2004 2004/01/01/;8(4):376-384.
- Ursini F, Heim S, Kiess M, et al. Dual function of the selenoprotein PHGPx during sperm maturation. Science. 1999;285(5432):1393-1396.
- Noack‐Füller G, De Beer C, Seibert H. Cadmium, lead, selenium, and zinc in semen of occupationally unexposed men. Andrologia. 1993;25(1):7-12.
- Nazari L, Salehpour S, Hosseini S, et al. Effect of antioxidant supplementation containing L-carnitine on semen parameters: a prospective interventional study. JBRA Assist Reprod. 2021 Feb 2;25(1):76-80.
- Lenzi A, Sgro P, Salacone P, et al. A placebo-controlled double-blind randomized trial of the use of combined l-carnitine and l-acetyl-carnitine treatment in men with asthenozoospermia. Fertility and sterility. 2004;81(6):1578-1584.
- Fraga CG, Motchnik PA, Shigenaga MK, et al. Ascorbic acid protects against endogenous oxidative DNA damage in human sperm. Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11003-6.
- Qamar AY, Naveed MI, Raza S, et al. Role of antioxidants in fertility preservation of sperm - A narrative review. Anim Biosci. 2023 Mar;36(3):385-403.
- Cyrus A, Kabir A, Goodarzi D, Moghimi M. The effect of adjuvant vitamin C after varicocele surgery on sperm quality and quantity in infertile men: a double blind placebo controlled clinical trial. Int Braz J Urol. 2015 Mar-Apr;41(2):230-8.
- Dawson EB, Harris WA, Teter MC, Powell LC. Effect of ascorbic acid supplementation on the sperm quality of smokers. Fertil Steril. 1992 Nov;58(5):1034-9.
- Henkel R, Samanta L, Agarwal A. Oxidants, antioxidants, and impact of the oxidative status in male reproduction. Academic Press; 2018.
- Keskes-Ammar L, Feki-Chakroun N, Rebai T, et al. Sperm oxidative stress and the effect of an oral vitamin E and selenium supplement on semen quality in infertile men. Arch Androl. 2003 Mar-Apr;49(2):83-94.
- Suleiman SA, Ali ME, Zaki ZM, et al. Lipid peroxidation and human sperm motility: protective role of vitamin E. J Androl. 1996 Sep-Oct;17(5):530-7.
- Kessopoulou E, Powers HJ, Sharma KK, et al. A double-blind randomized placebo cross-over controlled trial using the antioxidant vitamin E to treat reactive oxygen species associated male infertility. Fertil Steril. 1995 Oct;64(4):825-31.
- Therond P, Auger J, Legrand A, Jouannet P. α-Tocopherol in human spermatozoa and seminal plasma: relationships with motility, antioxidant enzymes and leukocytes. MHR: Basic science of reproductive medicine. 1996;2(10):739-744.
- Wong WY, Merkus HM, Thomas CM, et al. Effects of folic acid and zinc sulfate on male factor subfertility: a double-blind, randomized, placebo-controlled trial. Fertil Steril. 2002 Mar;77(3):491-8.
- Li X, Zeng Y-m, He J, et al. Effects of folic acid and folic acid plus zinc supplements on the sperm characteristics and pregnancy outcomes of infertile men: A systematic review and meta-analysis. Heliyon. 2023.
- Beltrame FL, Sasso-Cerri E. Vitamin B(12)-induced spermatogenesis recovery in cimetidine-treated rats: effect on the spermatogonia number and sperm concentration. Asian J Androl. 2017 Sep-Oct;19(5):567-572.
- Banihani SA. Vitamin B(12) and Semen Quality. Biomolecules. 2017 Jun 9;7(2).
- Hosseinabadi F, Jenabi M, Ghafarizadeh AA, Yazdanikhah S. The effect of vitamin B12 supplement on post-thaw motility, viability and DNA damage of human sperm. Andrologia. 2020 Dec;52(11):e13877.
- Allouche-Fitoussi D, Breitbart H. The Role of Zinc in Male Fertility. Int J Mol Sci. 2020 Oct 21;21(20).
- Kowalczyk A. The Role of the Natural Antioxidant Mechanism in Sperm Cells. Reproductive Sciences. 2022 2022/05/01;29(5):1387-1394.
- Reichart M, Lederman H, Har-Even D, et al. Human sperm acrosin activity with relation to semen parameters and acrosomal ultrastructure. Andrologia. 1993 Mar-Apr;25(2):59-66.
- Bermingham EN, Hesketh JE, Sinclair BR, et al. Selenium-enriched foods are more effective at increasing glutathione peroxidase (GPx) activity compared with selenomethionine: a meta-analysis. Nutrients. 2014 Sep 29;6(10):4002-31.