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Magnesium (HVP chelate)
Magnesium, in its highly bioavailable HVP chelate form, is a very important mineral involved in over 300 biochemical processes in the body1. This form of magnesium guarantees superior absorption and minimizes gastrointestinal discomfort, making it suitable for sensitive individuals2. Magnesium is essential for muscle relaxation and nerve function, helping to calm overactive neurons and reduce nervous system excitability3. It plays a significant role in stress management by lowering cortisol levels and stabilizing neurotransmitters such as GABA, thereby promoting relaxation and improving sleep quality4. In addition, magnesium promotes cardiovascular health by regulating blood pressure and reducing the impact of stress on the heart4. Magnesium deficiency has been associated with increased anxiety and high stress sensitivity, making its supplementation an effective strategy for relaxation and stress relief5.
Vitamin B6 (Pyridoxine HCL)
Vitamin B6, or pyridoxine hydrochloride, is essential for neurotransmitter synthesis and protein metabolism, directly influencing mood regulation and cognitive function6. By supporting adrenal gland function, vitamin B6 helps regulate the body's response to stress, maintaining balanced cortisol levels and reducing symptoms of anxiety and irritability7. This vitamin is particularly beneficial in alleviating mood swings and other premenstrual symptoms, as it helps modulate hormone levels8. In addition, vitamin B6 contributes to cognitive health by supporting the formation of myelin, which protects nerve cells and improves their communication9. Together with magnesium, it forms a synergistic combination that strengthens resilience in the face of stress and promotes relaxation, making Prozen an effective natural option for stress and mood management10.
VISIT OUR HEALTH RESOURCES SECTION TO LEARN MORE ABOUT THESE SPECIFIC INGREDIENTS

Why choose Prozen?
This supplement is indicated for patients suffering from disorders associated with magnesium and vitamin B6 deficiency in men and women (nervous and/or muscular fatigue, irritability, transient tiredness, minor sleep disorders, palpitations, muscle cramps, tingling, pain associated with premenstrual syndrome, menstruation and migraines). The combination of vitamin B6 and magnesium may be more effective (than either treatment alone) against PMS symptoms.
Also indicated for pregnant women with pregnancy-related morning sickness, stress and fatigue.
How do I take my treatment?
1 capsule 3 times a day, with food a few hours before or after taking other medications.
How long should I take Prozen?
Prozen is a natural supplement that should be taken on a daily basis for an indefinite period of time. We therefore recommend that you make it part of your daily routine.
When should I stop taking Prozen?
Prozen can be taken daily for an indefinite period. However, it is important to stop taking it if your doctor recommends it.
Use of this supplement may be considered during pregnancy, if necessary. Ask your doctor or pharmacist for advice.
It is recommended not to exceed 20mg/day of vitamin B6 for breast-feeding women. Ask your doctor or pharmacist for advice.
Some people may develop diarrhea.
Contraindicated in cases of severe renal insufficiency (impaired kidney function).
- de Baaij, J. H., Hoenderop, J. G. & Bindels, R. J. Magnesium in man: implications for health and disease. Physiol Rev 95, 1-46, doi:10.1152/physrev.00012.2014 (2015).
- Rosanoff A, Weaver CM, Rude RK. Suboptimal magnesium status in the United States: are the health consequences underestimated? Nutr Rev. Mar 2012;70(3):153-64. doi:10.1111/j.1753-4887.2011.00465.x
- Barbagallo M, Dominguez LJ. Magnesium and aging. Curr Pharm Des. 2010;16(7):832-9. doi:10.2174/138161210790883679
- Boyle NB, Lawton C, Dye L. The Effects of Magnesium Supplementation on Subjective Anxiety and Stress-A Systematic Review. Nutrients. Apr 26 2017;9(5)doi:10.3390/nu9050429
- Jacka FN, Overland S, Stewart R, Tell GS, Bjelland I, Mykletun A. Association between magnesium intake and depression and anxiety in community-dwelling adults: the Hordaland Health Study. Aust N Z J Psychiatry. Jan 2009;43(1):45-52. doi:10.1080/00048670802534408
- Przybelski AG, Bendlin BB, Jones JE, Vogt NM, Przybelski RJ. Vitamin B6 and vitamin D deficiency co-occurrence in geriatric memory patients. Alzheimers Dement (Amst). Jan-Mar 2024;16(1):e12525. doi:10.1002/dad2.12525
- Camfield DA, Wetherell MA, Scholey AB, et al. The effects of multivitamin supplementation on diurnal cortisol secretion and perceived stress. Nutrients. Nov 11 2013;5(11):4429-50. doi:10.3390/nu5114429
- Wyatt KM, Dimmock PW, Jones PW, Shaughn O'Brien PM. Efficacy of vitamin B-6 in the treatment of premenstrual syndrome: systematic review. Bmj. May 22 1999;318(7195):1375-81. doi:10.1136/bmj.318.7195.1375
- Combs Jr GF, McClung JP. The vitamins: fundamental aspects in nutrition and health. Academic press; 2016.
- Noah L, Dye L, Bois De Fer B, Mazur A, Pickering G, Pouteau E. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial. Stress Health. Dec 2021;37(5):1000-1009. doi:10.1002/smi.3051